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Tag: Medicine

  • Apigenin could kill 85% of lung cancer cells

    Lung cancer is defined as an uncontrolled reproduction of abnormal cells within the lung.

    Cancer cells will group themselves to form a lung tumor. If cancer cells manage to split and pass into the blood and lymphatic stream, they can reach other parts of the body to form metastases. This form of cancer is quite aggressive, evolving rapidly.

    Apigenin molecule (pic: wikimedia commons)
    Apigenin molecule (pic: wikimedia commons)
    Lung cancer is the most common malignancy in the world, with maximum incidence in men. In women, lung cancer is the second most common cancer after breast cancer.

    A 2013 study published in PubMed, a website of the National Institute of Health, revealed that apigenin, a substance usually found in parsley, can destroy 85% of lung cancer cells.
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    Apigenin or 4′,5,7-trihydroxyflavone (chemical formula‎: ‎C15H10O5) is a natural compound that is found also in other vegetables and fruits such as celery, celeriac, chamomile tea, oranges or onions which are the most common sources.

    Apigenin is particularly abundant in the flowers of chamomile plants, constituting 68% of total flavonoids.
    Photo credit: DFliyerz [CC BY-SA 4.0], via Wikimedia Commons

  • Effects of caffeine on human body in first hours after drinking coffee

    For many people, the coffee is a necessity, a mainstay of the morning ritual, something without which you can not kick off the day.

    But have you ever wondered what changes occur in your body after drinking a cup of coffee?

    Well, it appears that within the first 10 minutes, the caffeine enters the blood stream. The blood pressure starts to rise and the same happens with the heart beat rate.

    After 20 minutes, you feel more focused and alert. It is much easier to capture information, make decisions and solve problems. Moreover, the caffeine helps you feel less tired because of binding to adenosine receptors in the brain cells. Practically it reversibly blocks the action of adenosine on its receptor and consequently prevents the onset of drowsiness induced by adenosine.

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    40 minutes later, the serotonin levels begin to rise. This improves the functioning of neurons, leading to increased muscle strength.

    After four hours, the coffee acts on the cells and helps your body release energy. The body begins to burn fat even when you are at total rest. In addition, the caffeine stimulates and enhances the production of stomach acid.

    And finally, after six hours, the diuretic effect of caffeine emerges. Besides water, the body will lose also some essential vitamins and minerals. This may lead sometimes to progressive disorder of calcium in the metabolism.

  • Gold nanoparticles to detect HIV and prostate cancer with bare eye

    Gold nanoparticles used in prototype sensor for viewing diseases and viruses with naked eye. Photo:topnews.in
    British scientists have revealed a test based on gold nanoparticles which allows the eye to view early stages of a disease or a virus infection, such as prostate cancer or HIV.

    The novel detector comprises tiny gold particles deposited on a plastic support, enabling the analysis of the serum contained in the patient’s blood.

    If the serum contains distinctive biological markers of disease, such as p24, linked to infection with the virus that triggers AIDS, and prostate-specific antigen (PSA) that serves for diagnosis of prostate cancer, then the gold nanoparticles react, providing a blue tint characteristic to this solution which is analyzed by the detector. In the absence of these markers, the particles separate to form tiny bubbles that give solutions a reddish coloring.

    According to its inventors, the medical prototype is 10 times more sensitive than the previous tests and 10 times cheaper to manufacture. That should be enough to make poor countries interested in the new test.
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    “The test is designed on disposable plastic supports and does not require the use of expensive equipment, since the sought molecule can be detected at a quick glance with naked eye,” said Molly Stevens from Imperial College London.

    The high sensitivity of this prototype ultra-sensitive sensor makes it suitable for early stage detection of an infection or a disease, when current methods fail, thus providing a greater chance of treatment, e.g. to HIV-positive patients.

    “It is important for these patients to be tested periodically to assess the success of retroviral therapies and to detect new cases of infection,” said Roberto Rica, coauthor of the study, published today in the scientific journal Nature Nanotechnology.